Sure like the new 250 having a rear disc brake instead of a drum rear thats on the 225 and the new digital instrumentaion is cool.
For whatever reason they bumped the 250 down to a 5 speed.
I'll keep the 6 speed on my 225. It will cruise all day at a indicated 70mph (GPS says 66mph).
The new Yamaha WR250R (also a dual sport) does have a 6 speed and even fuel injection but it has a much larger price tag than the XT250 and would be better off road.
http://www.yamaha-motor.com/sport/products/modelimagelib/595/1/1/0/image.aspx